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Seattle Epidemiologic Research and Information Center (ERIC)


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Current Research

The Seattle ERIC supports epidemiologic research on the causes and outcomes of important health conditions among US Veterans by providing operational support. This section describes the current Seattle ERIC research portfolio of Cooperative Studies Program (CSP) projects.

CSP #256: Vietnam-Era Twin Registry

The Vietnam-Era Twin Registry was re-located to the Seattle ERIC in 2001 and it enhances the ability of the ERIC to achieve its goals. The VET Registry provides a unique sample of veterans for investigators to study the genetic and environmental determinates of diseases etiology and outcomes. Principal Investigator: Nicholas L. Smith, PhD. Project Manager: Cindy Liu.

CSP #595: Service and Health during the Iraq and Afghanistan Era

The primary objective of the full-scaled study is to characterize the impact of deployment to Iraq and Afghanistan on the respiratory health of Veterans. The purpose of the pilot study is to determine the willingness of Veterans who served during the Iraq and Afghanistan Era to provide health and military service information. This information will help us design a larger national study. For more information, see the CSP #595 website or use identifier NCT01987401 to look up the study on (a non-VA website). Study Chairs: Eric Garshick, MD, MOH and Susan Proctor, DSc. Center Director: Nicholas L. Smith, PhD. Project Manager: Karen Nakayama.

CSP #2007: National Vietnam Veterans Longitudinal Study (NVVLS) Registry

The Seattle Epidemiologic Research and Information Center (ERIC) acquired stewardship of the National Vietnam Veterans Longitudinal Study (NVVLS) Registry in April of 2015.  The Registry is a United States Department of Veterans Affairs (VA) resource that was originally constructed from National Vietnam Veterans Readjustment Study (NVVRS) data collected from 1986-1988, and the follow up study (NVVLS)  conducted from 2012-2013.  The NVVLS Registry is a closed cohort composed of approximately 1,450 female and male Veterans who served in the United Stated military during the time of the Vietnam War (1964-1975). Initially formed to look at the prevalence, incidence, and effects of Post-traumatic Stress Disorder (PTSD) and related postwar psychological issues, the Registry has evolved into a resource for epidemiologic studies of mental and physical health conditions. The NVVLS Registry’s goals include supporting and promoting scientific research of the Registry, safeguarding the Registry’s members and resources for future research, and maintaining a secure and updated Registry database, while treating our members with respect and maintaining their confidentiality.  The NVVLS Registry is open for access to qualified VA, VA-affiliated, and non-VA investigators working for not-for-profit, academic and research centers. Fees are based on services performed by the Registry to help you complete your study. See the Investigator Access page for more information. Principal Investigator: Nicholas L. Smith, PhD. Project Manager: Cindy Liu.

A Twin Study of the Course and Consequences of Post-Traumatic Stress Disorder in Vietnam Era Veterans (Cooperative Studies Program #569)

This study used the Vietnam-Era Twin (VET) Registry to examine the mental and physical health of Vietnam-era veterans as they age. The study was designed to estimate current prevalence of mental and physical health conditions and to answer questions about how PTSD might influence the lives of Veterans decades after the end of the war. The relationship between PTSD and cardiovascular disease, and PTSD and diabetes, were of particular interest. The study has been completed and findings are being published in scientific and medical journals.

Million Veteran Program (MVP) (Cooperative Studies Program #G002)

MVP is a national research program funded by the Department of Veterans Affairs Office of Research & Development to study how genes affect health.  The goal is to collect blood samples and health information from one million Veteran volunteers, which will be stored anonymously in a large database. For more information, and to find out how Veterans can participate in the study, please visit Seattle site contacts: Edward J. Boyko, MD, MPH and Amber Seelig, MPH.

Millennium Cohort Study (Cooperative Studies Program #505)

The primary objective of this study is to evaluate the impact of military service, including deployments and other occupational exposures, on long-term health. Important health outcomes include all objective diagnoses, as well as subjective measures of symptoms and functional health. For more information, please visit (a non-VA website). Seattle site contacts: Edward J. Boyko, MD, MPH and Amber Seelig, MPH.